PROGRAMME

Sunday, 22 August

3.00 p.m.

Registration opens (Main Lobby, Delta Lodge)

7.00 p.m.

Welcome Reception (Gold/Silver Ballroom)

Monday, 23 August

7.00 a.m.

Breakfast (Rockies)

8.00 a.m.

Opening Remarks (Gold/Silver Ballroom)
Gary Lopaschuk and Dale Abel

8.15 a.m.

Keynote Lecture (Gold/Silver Ballroom)

Junichi Sadoshima (Newark, NJ, USA)
Autophagy in myocardial ischemia and heart failure

 

Session I (Gold/Silver Ballroom)

Lipid signalling and insulin resistance in the heart
Chairs: Gary Lopaschuk and Dale Abel

9.00 a.m.

Jan Glatz (Maastricht, Netherlands)
CD36 and fate of fatty acids in heart

9.30 a.m.

E. Dale Abel (Salt Lake City, UT, USA)
Insulin resistance and lipotoxicity

10.00 a.m.

Brian Rodrigues (Vancouver, BC, Canada)
Fatty acid delivery to the heart following diabetes: role of lipoprotein lipase

10.30 a.m.

Coffee break (Convention Foyer)

 

Session II (Gold/Silver Ballroom)

Young Investigator Presentations
Chairs: Michael Allard and Terje Larsen

11.00 a.m.

Kalyani Bharadwaj (New York, NY, USA)
Chylomicron- and VLDL-derived fatty acids enter the heart through different pathways

11.15 a.m.

Jessica Ellis (Chapel Hill, NC, USA)
Mouse cardiac acyl-CoA synthetase-1 deficiency impairs fatty acid oxidation and induces hypertrophy and mitochondrial biogenesis

11.30 a.m.

Clifford Folmes (Rochester, MN, USA)
Nuclear reprogramming induces a glycolytic metabotype in induced pluripotent stem cells

11.45 a.m.

Petra Caroline Kienesberger (Edmonton, AB, Canada)
Chronic reduction in cardiac triacylglycerol content promotes enhanced myocardial contractility

12 noon

Lunch (Rockies)

1.00 p.m.

Poster Session I (Gold/Silver Ballroom)

 

Session III (Gold/Silver Ballroom)
Keeping the balance: metabolic signalling in heart failure Chair: Heinrich Taegtmeyer

2.30 p.m.

Genevieve Sparagna (Boulder, CO, USA)
Targeting cardiolipin with dietary treatments for heart failure

3.00 p.m.

Ravichandran Ramasamy (New York, NY, USA)
Aldose reductase and myocardial ischemia-reperfusion injury

3.30 p.m.

Adam Chicco (Fort Collins, CO, USA)
Role of delta-6 desaturase in aberrant cardiolipin remodeling, mitochondrial dysfunction and lipoxidative stress the failing heart

3.45 p.m.

Coffee break (Convention Foyer)

4.15 p.m.

Craig Lygate (Oxford, United Kingdom)
The creatine kinase system as a therapeutic target: challenges and opportunities

4.45 p.m.

John Ussher (Toronto, ON, Canada)
Enhanced lifespan is malonyl CoA decarboxylase mice is associated with decreased whole body fatty acid oxidation

5.00 p.m.

Dake Qi (New Haven, CT, USA)
AMP-activated protein kinase limits the activation of c-Jun N terminal kinase and prevents cardiac reperfusion injury

 

Monday Evening: Shuttle Departures to Boundary Ranch (parking available for those who wish to drive)

6.00 p.m.

Main entrance – Delta Kananaskis Lodge (1st shuttle)

6:20 p.m.

Main entrance – Delta Kananaskis Lodge (2nd shuttle)

6.30 p.m.

Boundary Ranch Western Barbeque & Rodeo

Tuesday, 24 August

7.00 a.m.

Breakfast (Rockies)

 

Session IV (Gold/Silver Ballroom)

Insulin and hormonal signaling
Chairs: Martin Young and Margaret Chandler

8.00 a.m.

Anne Murphy (San Diego, CA, USA)
Akt signaling and mitochondrial hexokinase

8.30 a.m.

Ping Wang (Irvine, CA, USA)
Insulin stimulates Akt1 translocation to mitochondria and modulates oxidative phosphorylation and apoptosis in cardiac muscle

9.00 a.m.

Michael Sack (Bethesda, MD, USA)
The role of protein acetylation in the interaction between mitochondrial dysfunction and insulin resistance

9.30 a.m.

Sabrina Greulich (Duesseldorf, Germany)
Crosstalk between epicardial fat and the heart in patients with type 2 diabetes

9.45 a.m.

Guorong Lin (Vancouver, BC, Canada)
Localization of ROCK2 in mitochondria: possible contribution to diabetic cardiomyopathy

10.00 p.m.

Coffee break (Convention Foyer)

10.30 p.m.

Poster Session II (Gold/Silver Ballroom)

12 noon

Lunch (Rockies)

 

Session V (Gold/Silver Ballroom)
Protective metabolic signalling: role of the mitochondria
Chairs: Fabio Di Lisa and PeiPei Ping

1.00 p.m.

Joy McCarthy (Cape Town, South Africa)
Altered fuel substrate selection required for PKCε cardioprotection

1.30 p.m.

Keith Garlid (Portland, OR, USA)
Cardioprotective intramitochondrial signaling

2.00 p.m.

Fabio Di Lisa (Padua, Italy)
Mitochondrial permeability transition and cardioprotection

2.30 p.m.

Timothy DeGrado (Needham, MA, USA)
Imaging fatty acid oxidation in the heart

3.00 p.m.

Afternoon free for Exploration and Relaxation

8.00 p.m.

Evening Gala Banquet (Olympic Ballroom)

Tribute to Howard Morgan and James Neely
Gary Lopaschuk (Edmonton, AB, Canada)

Wednesday, 25 August

7.00 a.m.

Breakfast (Rockies)

8.00 a.m.

Keynote Lecture (Gold/Silver Ballroom)

PeiPei Ping (Los Angeles, CA, USA)
The function and dynamics of mitochondrial proteome in cardioprotection

 

Session VI (Gold/Silver Ballroom)

Molecular signaling cascades involved in metabolic and growth regulation
Chairs: Brian Rodrigues and Craig Lygate

9.00 a.m.

Rosalind Coleman (Chapel Hill, NC, USA)
Acyl CoA synthetase & cardiac function

9.30 a.m.

Luc Bertrand (Brussels, Belgium)
Amino acid regulation of PDK1 & protein synthesis

10.00 a.m.

Maria Febbraio (Cleveland, OH, USA)
Role of CD36 in Vascular Function & Atherosclerosis

10.30 a.m.

David Symons (Salt Lake City, UT, USA)
Ceramide-induced impairment of endothelial nitric oxide synthase function in bovine aortic endothelial cells (BAECs) is not secondary to defective upstream signaling kinases or peroxynitrite formation

10.45 a.m.

Monte Willis (Chapel Hill, NC, USA)
Cardiac Muscle Ring Finger-1 (MuRF1) alters myocardial mitochondrial capacity in vivo

11.00 a.m.

Ji Li (Buffalo, NY, USA)
The cardioprotective effect of activated protein C is separate from its anticoagulant activity

11.15 a.m.

Closing Remarks (Gold/Silver Ballroom)
Gary Lopaschuk, Dale Abel, and Luc Bertrand

11.30 a.m.

Lunch (Rockies)

Important dates

  • Registrations and abstract submissions open
    February 25, 2010
  • Notification of abstract selections
    July 9, 2010
    Participants who submitted abstracts are currently being contacted; final notifications will be concluded by 14 July – please be patient...

 

Deadlines

  • Abstract submissions
    June 14, 2010
  • Early bird registrations
    June 14, 2010

 

Organising Committee  

Gary Lopaschuk (Chair)

Edmonton, Alberta

E. Dale Abel (Co-Chair)

Salt Lake City, UT

Mike Allard

Vancouver, British Columbia

Jason Dyck

Edmonton, Alberta